Research
Read plain-language study explanations, evidence reviews and research guides. Learn to interpret methods, uncertainty and clinical trial records.
Read the evidence, then see what it means.
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Showing 1–10 of 23 articles
Research guide
Published:
Learn what a p-value means, why p < 0.05 does not prove a finding, and how effect sizes, confidence intervals and multiple testing change the interpretation.
Evidence review
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Compare intermittent fasting with daily calorie restriction using randomized trials and recent reviews, including weight loss, adherence and safety limits.
Evidence review
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What trials show about creatine with resistance training in older adults, including strength, lean mass, physical function, bone health and safety.
Evidence review
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Review the human evidence for NMN and NR: NAD levels, insulin sensitivity, cognition, walking ability and the gap between biomarkers and longer life.
Research guide
Published:
Learn to spot confounding and reverse causation, understand adjusted results and ask better questions about observational health research.
Research explained
Published:
A 2026 Neuron study improved memory by partially reprogramming selected mouse neurons. What changed, why it matters, and what remains unproven in humans.
Evidence review
Published:
Compare the evidence for oral collagen, hydration, elasticity and wrinkles, including study quality, funding, practical benefits and product limitations.
Research explained
Published:
A 2026 study targets LINE-1 activity in aging mouse hearts. Understand the experiment, why the result matters and what remains unproven in humans.
Research guide
Published:
Use confidence intervals to judge effect size, precision, compatibility with benefit or harm, and the limits of repeated-study interpretation.
Research guide
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Translate relative risk, absolute difference, number needed to treat, baseline risk, time horizon, and competing harms into decisions.
Evidence review
Published:
What randomized reviews support about exercise for depression, where confidence falls, and how to place activity inside complete care.
Research explained
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Interpret the 2024 BMJ network meta-analysis of exercise modalities through effect size, study quality, adherence, and treatment context.
Research explained
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Interpret SELECT’s cardiovascular result, absolute event difference, discontinuation, funding, eligibility, and unanswered questions.
Research explained
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Understand why ACHIEVE’s overall neutral result and prespecified higher-risk subgroup result must be held together.
Research explained
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Understand the DASH trial’s controlled meals, comparison patterns, blood-pressure changes, short duration, and real-world translation.
Research explained
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Interpret SPRINT’s benefits, adverse events, measurement method, selected population, and why its target cannot be copied without context.
Research guide
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A repeatable route through the question, design, participants, comparison, outcomes, missing data, results, limitations, and conflicts.
Evidence review
Published:
A practical synthesis of sodium reduction, blood-pressure response, food sources, measurement, and situations requiring individualized advice.
Research explained
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Read the STEP 1 semaglutide trial through average change, response variation, adverse effects, treatment duration, and generalizability.
Research explained
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Read the Mediterranean-diet trial alongside its randomization problems, reanalysis, event numbers, and limits on generalization.
Research guide
Published:
Use registration, assignment, masking, comparators, outcomes, analysis, adverse events, and participant flow to understand a trial.
Evidence review
Published:
Separate eating fish, ordinary fish-oil supplements, and prescription omega-3 products when assessing cardiovascular evidence and risk.
Research explained
Published:
A public reading of the landmark trial comparing intensive lifestyle support, metformin, and placebo in people at high diabetes risk.
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